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Claudin-6 Rabbit pAb

Catalog Number:OM646384
OM646384
Discount Price
OM646384-100ul
100ul
Product Profile
Product Name Claudin-6 Rabbit pAb
Antibody Type Primary Antibodies
Immunogen The antiserum was produced against synthesized peptide derived from human CLDN6. AA range:81-130
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHCWB
WB:1:500-1:2000
IHC:1:100-1:300
ICC/IF:1:200-1:1000
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CLDN6
Gene Full Name claudin 6
Gene Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
Alternative Names CLDN6
Claudin-6
Skullin
Molecular Weight(MW) 26 kDa
Cellular Localization Cell junction , tight junction . Cell membrane ; Multi-pass membrane protein .
Application

WB

Western Blot analysis of various cells using Claudin-6 Polyclonal Antibody.

WB

Western blot analysis of lysates from Jurkat cells, using CLDN6 Antibody. The lane on the right is blocked with the synthesized peptide.

IHC

Immunohistochemistry analysis of paraffin-embedded human ovary tissue, using CLDN6 Antibody. The picture on the right is blocked with the synthesized peptide.

ICC/IF

Immunofluorescence analysis of HUVEC cells, using CLDN6 Antibody. The picture on the right is blocked with the synthesized peptide.
Application Notes WB:1:500-1:2000
IHC:1:100-1:300
ICC/IF:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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