Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-IL-6 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality
Monoclonal
Isotype
IgG,K
Host Species
Rabbit
Tested Applications
WB
WB:1:2000-1:10000
Species Reactivity
Mouse
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
IL6
Gene Synonyms
CDF HGF HSF BSF2 IL-6 BSF-2 IFNB2 IFN-beta-2
Gene Full Name
interleukin 6
Gene Summary
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020]
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-IL-6 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.