This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
Alternative Names
TAU MSTD PPND DDPAC MAPTL MTBT1 MTBT2 FTDP-17 PPP1R103
Molecular Weight(MW)
79 kDa(Observed MW: 50-80 kDa)
Application
WB
Western blot analysis of extracts from Human hippocampus tissue using Phospho-Tau (Ser202/Thr205) Rabbit mAb at 1:1000.
Application Notes
WB:1:1000 IP:1:20-1:50
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C.Stable for 12 months from date of receipt.
Storage Buffer
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA