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Rat Monoclonal antibody to Fibroblast Marker

Catalog Number:OM646452
Human;Mouse;Rat
WB
OM646452
Discount Price
OM646452-100ul
100ul
Product Profile
Product Name Rat Monoclonal antibody to Fibroblast Marker
Antibody Type Primary Antibodies
Immunogen raised against a thymic reticulum of mouse origin.
Key Feature
Clonality Monoclonal
Isotype IgG2a
Host Species Rat
Tested Applications WB
WB:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Function Fibroblast cells synthesize and maintain the extracellular matrix in a wide variety of mammal tissues. Fibroblasts provide a structural framework for many tissues and also play an important role in wound healing. They are con tinuously secreting precursors of the extracellular matrix, specifically the col lagens, glycosaminoglycans, reticular and elastic fibers and glycoproteins. Fibroblasts are morphologically heterogeneous and are not restricted by a polarizing attachment to a basal lamina. Fibroblasts have a branched cyto plasm surrounding an elliptical, speckled nucleus having one or two nucleoli. Fibroblasts proliferate easily, making them a popular cell type for cell cultures in biological research. Fibroblast markers can aid in the identification and behavioral analysis of these cells. The intermediate filament protein vimentin, for example, is expressed on Fibroblast cells, and it is used as a marker to distinguish the mesodermal origin of the cells.
Application

WB

FibroblastMarker HRP:Rat Monoclonal antibody to Fibroblast Marker.Direct westernblotanalysisofFibroblastMarkerexpression in3611-RFwholecell lysate.
Application Notes WB:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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