The membrane was blotted with anti-TMEM173 (Phospho Ser365)
antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was
used to detect the antibody.
The specific immunogen used to produce this antibody is proprietary information.
Modification
p-Ser365
Key Feature
Clonality
Monoclonal
Isotype
IgG,K
Host Species
Rabbit
Tested Applications
WB
WB:1:1000-1:5000
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
STING1
Gene Synonyms
ERIS MITA MPYS SAVI NET23 STING hMITA hSTING TMEM173 STING-beta
Gene Full Name
stimulator of interferon response cGAMP interactor 1
Gene Summary
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Alternative Names
TMEM173 ERIS MITA STING Transmembrane protein 173 Endoplasmic reticulum interferon stimulator ERIS Mediator of IRF3 activation hMITA Stimulator of interferon genes protein hSTING
Molecular Weight(MW)
42 kDa(Observed band size: 37 kDa)
Cellular Localization
Nucleus.
Application
WB
The membrane was blotted with anti-TMEM173 (Phospho Ser365)
antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was
used to detect the antibody.