Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-RIP (Phospho Ser166) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
The specific immunogen used to produce this antibody is proprietary information.
Modification
p-Ser166
Key Feature
Clonality
Monoclonal
Isotype
IgG,K
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
MouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
RIPK1
Gene Synonyms
RIP RIP1 AIEFL IMD57 RIP-1
Gene Full Name
receptor interacting serine/threonine kinase 1
Gene Summary
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]
Alternative Names
Receptor-interacting serine/threonine-protein kinase 1
Cell death protein RIP
Receptor-interacting protein 1
RIP-1
Serine/threonine-protein kinase RIP
Molecular Weight(MW)
76 kDa(Observed band size: 70 kDa)
Cellular Localization
Cytoplasm . Cell membrane.
Application
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-RIP (Phospho Ser166) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.