Recombinant Rabies virus Glycoprotein protein (20-459AA)
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:1000-1:5000
Species Reactivity
Virus
Concentration
1mg/ml
Purification
Protein G
Target Information
Gene Symbol
G
Target
Rabies virus
Alternative Names
GGlycoprotein antibody
Molecular Weight(MW)
55 kDa
Function
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Application
WB
All lanes: Rabies virus Glycoprotein (G) antibody at 1: 500,
Lane 1: Rabies virus antigen 1: 2,
Lane 2: Rabies virus antigen 1: 10,
Lane 3: Rabies virus antigen 1: 20,
Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution.
Application Notes
WB:1:1000-1:5000
Additional Information
Form
Liquid
Storage Instructions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.