Recombinant fusion protein of human STARD4. The exact sequence is proprietary.
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:1000
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
STARD4
Gene Full Name
StAR related lipid transfer domain containing 4
Gene Summary
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]
Alternative Names
StAR-related lipid transfer protein 4 START domain-containing protein 4 StARD4
Molecular Weight(MW)
23 kDa
Cellular Localization
Cytoplasm,Endoplasmic reticulum.
Application
WB
Western blot analysis of STARD4 expression in HEK293 (A)
whole cell lysates.
Application Notes
WB:1:500-1:1000
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in PBS, pH 7.3, 50% glycerol, 0.05% BSA, and 0.05% Proclin300.