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Cdk2/Cdc2 (Phospho Thr160) Rabbit pAb

Catalog Number:OM646774
OM646774
Discount Price
OM646774-100ul
100ul
Product Profile
Product Name Cdk2/Cdc2 (Phospho Thr160) Rabbit pAb
Antibody Type Primary Antibodies
Immunogen Synthesized phospho-peptide around the phosphorylation site of human Cdk2/Cdc2 (phospho Thr160).
Modification p-Thr160
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
WB:1:500-1:2000
IHC:1:100-1:300
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CDK2
Gene Synonyms CDKN2
p33(CDK2)
Gene Full Name cyclin dependent kinase 2
Gene Summary This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Alternative Names CDK2
CDKN2
Cyclin-dependent kinase 2
Cell division protein kinase 2
p33 protein kinase
Molecular Weight(MW) 34 kDa
Cellular Localization Cytoplasm , cytoskeleton , microtubule organizing center , centrosome. Nucleus , Cajal body. Cytoplasm. Endosome. Localized at the centrosomes in late G2 phase after separation of the centrosomes but before the start of prophase. Nuclear-cytoplasmic trafficking is mediated during the inhibition by 1 ,25- (OH) (2) D (3) .
Application

WB

Western Blot analysis of various cells using Phospho-Cdk2/Cdc2 (T160) Polyclonal Antibody diluted at 1:500.

IHC

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4℃ overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
Application Notes WB:1:500-1:2000
IHC:1:100-1:300
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year (Do not lower than -25°C).
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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