WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-STAT6 (Phospho Tyr641) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.IHC
Human liver was stained with anti-STAT6 (Phospho Tyr641) Rabbit antibody.IHC
Mouse kidney was stained with anti-STAT6 (Phospho Tyr641) Rabbit antibody.IHC
Rat kidney was stained with anti-STAT6 (Phospho Tyr641) Rabbit antibody.| Product Name | STAT6 (Phospho Tyr641) Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Modification | p-Tyr641 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG,K |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:2000-1:10000 IHC:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | STAT6 |
|---|---|
| Gene Synonyms | HIES6 STAT6B STAT6C D12S1644 IL-4-STAT |
| Gene Full Name | signal transducer and activator of transcription 6 |
| Gene Summary | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| Alternative Names | STAT6 Signal transducer and activator of transcription 6 IL-4 Stat |
| Molecular Weight(MW) | 94 kDa(Observed band size: 110 kDa) |
| Cellular Localization | Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation. |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-STAT6 (Phospho Tyr641) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
IHC
Human liver was stained with anti-STAT6 (Phospho Tyr641) Rabbit antibody.
IHC
Mouse kidney was stained with anti-STAT6 (Phospho Tyr641) Rabbit antibody.
IHC
Rat kidney was stained with anti-STAT6 (Phospho Tyr641) Rabbit antibody.| Application Notes | WB:1:2000-1:10000 IHC:1:500-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year (Do not lower than -25°C). |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA. |
