IHC
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using Rabbit anti-ERG Polyclonal antibody at dilution of 1:100.ICC/IF
Immunofluorescent analysis of PC-3 cells using Rabbit anti-ERG Polyclonal antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).IP
Immunoprecipitating ERG in Rat heart tissue.| Product Name | Rabbit anti-ERG Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Transcriptional regulator ERG protein (1-486AA). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIP |
| IHC:1:20-1:200 ICC/IF:1:50-1:200 IP:1:200-1:2000 |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | ERG |
|---|---|
| Gene Synonyms | p55 erg-3 LMPHM14 |
| Gene Full Name | ETS transcription factor ERG |
| Gene Summary | This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Apr 2014] |
| Alternative Names | Avian erythroblastosis virus E-26 (v-ets) oncogene related antibody D030036I24Rik antibody Erg 3 antibody Erg antibody ERG/EWS fusion gene included antibody ERG/FUS fusion gene included antibody ERG/TMPSSR2 fusion gene included antibody ERG_HUMAN antibody ERG1 included antibody ERG2 included antibody ets related antibody ETS-related gene antibody KCNH2 antibody Oncogene ERG antibody p55 antibody TMPRSS2/ERG fusion antibody transcriptional regulator ERG (transforming protein ERG) antibody Transcriptional regulator ERG antibody Transforming protein ERG antibody v ets avian erythroblastosis virus E26 oncogene antibody v ets avian erythroblastosis virus E26 oncogene related antibody v ets erythroblastosis virus E26 oncogene homolog antibody v ets erythroblastosis virus E26 oncogene like antibody v ets erythroblastosis virus E26 oncogene like isoform 2 antibody v-ets erythroblastosis virus E26 oncogene antibody v-ets erythroblastosis virus E26 oncogene homolog (avian) antibody V-ets erythroblastosis virus E26 oncogene like (Avian) isoform CRA_e antibody |
| Cellular Localization | Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
IHC
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using Rabbit anti-ERG Polyclonal antibody at dilution of 1:100.
ICC/IF
Immunofluorescent analysis of PC-3 cells using Rabbit anti-ERG Polyclonal antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IP
Immunoprecipitating ERG in Rat heart tissue.| Application Notes | IHC:1:20-1:200 ICC/IF:1:50-1:200 IP:1:200-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
