Western blot analysis of lysates from Mouse testis, using ARNT2 Antibody at 1/1000 dilution.
5ug/NC membrane strip.
Exposure for 10s with ECL Kit.
Bands result from membrane strip incubation.
A synthesized peptide derived from human ARNT2, corresponding to a region within N-terminal amino acids.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:1000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
ARNT2
Gene Synonyms
WEDAS bHLHe1
Gene Full Name
aryl hydrocarbon receptor nuclear translocator 2
Gene Summary
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013]
Alternative Names
ARNT protein 2 ARNT2 ARNT2_HUMAN Aryl hydrocarbon receptor nuclear translocator 2 bHLHe1 Class E basic helix-loop-helix protein 1
Molecular Weight(MW)
79 kDa
Cellular Localization
Nucleus.
Application
WB
Western blot analysis of lysates from Mouse testis, using ARNT2 Antibody at 1/1000 dilution.
5ug/NC membrane strip.
Exposure for 10s with ECL Kit.
Bands result from membrane strip incubation.
Application Notes
WB:1:500-1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at -20 °C. Stable for 12 months from date of receipt.
Storage Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.