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Rabbit polyclonal antibody to ARNT2
Catalog Number:OM647010
OM647010
Discount Price
OM647010-100ul
100ul
OM647010-50ul
50ul
Product Profile
Product Name Rabbit polyclonal antibody to ARNT2
Antibody Type Primary Antibodies
Immunogen A synthesized peptide derived from human ARNT2, corresponding to a region within N-terminal amino acids.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ARNT2
Gene Synonyms WEDAS
bHLHe1
Gene Full Name aryl hydrocarbon receptor nuclear translocator 2
Gene Summary This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013]
Alternative Names ARNT protein 2
ARNT2
ARNT2_HUMAN
Aryl hydrocarbon receptor nuclear translocator 2
bHLHe1
Class E basic helix-loop-helix protein 1
Molecular Weight(MW) 79 kDa
Cellular Localization Nucleus.
Application

WB

Western blot analysis of lysates from Mouse testis, using ARNT2 Antibody at 1/1000 dilution. 5ug/NC membrane strip. Exposure for 10s with ECL Kit. Bands result from membrane strip incubation.
Application Notes WB:1:500-1:1000
Additional Information
Form Liquid
Storage Instructions Store at -20 °C. Stable for 12 months from date of receipt.
Storage Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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