WB
Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-PIEZO1 antibody. The HRP conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.| Product Name | PIEZO1 Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG,K |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PIEZO1 |
|---|---|
| Gene Synonyms | ER DHS Mib LMPH3 FAM38A LMPHM6 |
| Gene Full Name | piezo type mechanosensitive ion channel component 1 (Er blood group) |
| Gene Summary | The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis. [provided by RefSeq, Jul 2015] |
| Alternative Names |
Piezo-type mechanosensitive ion channel component 1 Membrane protein induced by beta-amyloid treatment Mib Protein FAM38A |
| Molecular Weight(MW) | 287 kDa |
| Cellular Localization | Endoplasmic reticulum membrane ; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane . Cell membrane ; Multi-pass membrane protein . Cell projection , lamellipodium membrane . Cell membrane ; Multi-pass membrane protein. In erythrocytes , located in the plasma membrane (PubMed:22529292 , PubMed:23479567) . Accumulates at the leading apical lamellipodia of endothelial cells in response to shear stress (PubMed:25119035) . Colocalizes with F-actin and MYH9 at the actomyosin cortex in myoblasts. . |
WB
Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-PIEZO1 antibody. The HRP conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.| Application Notes | WB:1:500-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year (Do not lower than -25°C). |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA. |
