WB
Figure. Western Blot; Sample: Mouse Liver Tissue.IHC
DAB staining on IHC-P; Sample: Mouse Lung Tissue; Primary Ab: 20ug/ml Rabbit Anti-Mouse SP-B Antibody. Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.| Product Name | Polyclonal Antibody to Surfactant Protein B (SP-B) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant SP-B (Gly20~Pro193) expressed in E.coli. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:0.01-2µg/mL IHC:5-20µg/mL |
|
| Species Reactivity | Mouse |
| Concentration | 0.5mg/ml |
| Purification | Protein A |
| Gene Symbol | SFTPB |
|---|---|
| Gene Synonyms | SP-B PSP-B SFTB3 SFTP3 SMDP1 |
| Gene Full Name | surfactant protein B |
| Gene Summary | This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010] |
| Alternative Names | SFTPB PSPB SFTB3 SFTP3 SPB Surfactant Associated Protein B Pulmonary Surfactant Protein B 18 kDa pulmonary-surfactant protein 6 kDa protein |
| Molecular Weight(MW) | 42 kDa |
| Cellular Localization | Secreted,Surface film. |
WB
Figure. Western Blot; Sample: Mouse Liver Tissue.
IHC
DAB staining on IHC-P; Sample: Mouse Lung Tissue; Primary Ab: 20ug/ml Rabbit Anti-Mouse SP-B Antibody. Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.| Application Notes | WB:0.01-2µg/mL IHC:5-20µg/mL |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. |
| Storage Buffer | Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol. |
