This gene encodes a type II membrane glycoprotein which is one of the components of the renal amino acid transporter which transports neutral and basic amino acids in the renal tubule and intestinal tract. Mutations and deletions in this gene are associated with cystinuria. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Alternative Names
RBAT Neutral and basic amino acid transport protein rBAT NBAT D2h Solute carrier family 3 member 1 b(0 +)-type amino acid transport protein
Molecular Weight(MW)
79 kDa
Cellular Localization
Cell membrane,Membrane.
Application
WB
Western blot analysis of SLC3A1 expression in HT29 (A), HepG2 (B), PC12 (C), mouse liver (D) whole cell lysates.
IHC
Immunohistochemical analysis of SLC3A1 staining in rat kidney formalin fixed paraffin embedded tissue section.