WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Active Catenin β (Non phospho Ser45) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.IHC
Rat colon was stained with anti-Active Catenin β (Non phospho Ser45) Rabbit antibody.IHC
Human colon was stained with anti-Active Catenin β (Non phospho Ser45) Rabbit antibody.IHC
Mouse colon was stained with anti-Active Catenin β (Non phospho Ser45) Rabbit antibody.| Product Name | Active Catenin β (Non phospho Ser45) Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG,K |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:2000-1:10000 IHC:1:200-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CTNNB1 |
|---|---|
| Gene Synonyms | EVR7 CTNNB MRD19 NEDSDV armadillo |
| Gene Full Name | catenin beta 1 |
| Gene Summary | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] |
| Alternative Names | CTNNB1 CTNNB OK/SW-cl.35 Catenin beta-1 Beta-catenin |
| Molecular Weight(MW) | 86 kDa(Observed band size: 92 kDa) |
| Cellular Localization | Membrane , Cytoplasm. |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Active Catenin β (Non phospho Ser45) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
IHC
Rat colon was stained with anti-Active Catenin β (Non phospho Ser45) Rabbit antibody.
IHC
Human colon was stained with anti-Active Catenin β (Non phospho Ser45) Rabbit antibody.
IHC
Mouse colon was stained with anti-Active Catenin β (Non phospho Ser45) Rabbit antibody.| Application Notes | WB:1:2000-1:10000 IHC:1:200-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year (Do not lower than -25°C). |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA. |
