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Raptor (Phospho Ser792) Rabbit mAb

Catalog Number:OM647612
OM647612
Discount Price
OM647612-100ul
100ul
OM647612-50ul
50ul
Product Profile
Product Name Raptor (Phospho Ser792) Rabbit mAb
Antibody Type Primary Antibodies
Immunogen Raptor (Phospho Ser792)(PT1403R) Rabbit mAb.
Modification p-Ser792
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications WB
WB:1:2000-1:10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol RPTOR
Gene Synonyms KOG1
Mip1
Gene Full Name regulatory associated protein of MTOR complex 1
Gene Summary This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Alternative Names Regulatory-associated protein of mTOR
Raptor
p150 target of rapamycin
TOR
-scaffold protein
Molecular Weight(MW) 149 kDa(Observed band size: 150 kDa)
Cellular Localization Cytoplasm. Lysosome. Cytoplasmic granule . Targeting to lysosomes depends on amino acid availability. In arsenite-stressed cells , accumulates in stress granules when associated with SPAG5 and association with lysosomes is drastically decreased.
Database Links
SwissProt ID Q8N122
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Raptor (Phospho Ser792) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
Application Notes WB:1:2000-1:10000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year (Do not lower than -25°C).
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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