Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-PDK4 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality
Monoclonal
Isotype
IgG,K
Host Species
Rabbit
Tested Applications
WB
WB:1:2000-1:10000
Species Reactivity
MouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PDK4
Gene Full Name
pyruvate dehydrogenase kinase 4
Gene Summary
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008]
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-PDK4 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.