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HTR2A | 5HT2A Receptor Rabbit pAb

Catalog Number:OM647658
OM647658
Discount Price
OM647658-100ul
100ul
Product Profile
Product Name HTR2A | 5HT2A Receptor Rabbit pAb
Antibody Type Primary Antibodies
Immunogen KLH conjugated synthetic peptide derived from human 5HT2A Receptor : 51-150/471 .
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IF-PWB
WB:1:500-1:2000
IF-P:1:100-1:500
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol HTR2A
Gene Synonyms HTR2
5-HT2A
Gene Full Name 5-hydroxytryptamine receptor 2A
Gene Summary This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Alternative Names 5-HT2A
HTR2
5-HT-2
5-HT-2A
E030013E04
Htr-2
5Ht-2
5HT2A_HUMAN
HTR2A
Serotonin receptor 2A
5HT2A_MOUSE
5HT2A_RAT
5-hydroxytryptamine receptor 2A
5-hydroxytryptamine (serotonin) receptor 2A
5-hydroxytryptamine (serotonin) receptor 2A
G protein-coupled
Molecular Weight(MW) 53 kDa
Cellular Localization Cell membrane,Cell projection,Cytoplasmic vesicle,Membrane,Synapse.
Database Links
SwissProt ID P28223
Application

WB

Primary: Anti-5HT2A Receptor at 1/300 dilution. Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution.

IF-P

Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with 5HT2A Receptor Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C. Followed by conjugated Goat Anti-Rabbit IgG antibody (green), DAPI (blue) was used to stain the cell nuclei.

IF-P

Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with 5HT2A Receptor Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C. Followed by conjugated Goat Anti-Rabbit IgG antibody (green), DAPI (blue) was used to stain the cell nuclei.

IF-P

Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with 5HT2A Receptor Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C. Followed by conjugated Goat Anti-Rabbit IgG antibody (green), DAPI (blue) was used to stain the cell nuclei.
Application Notes WB:1:500-1:2000
IF-P:1:100-1:500
Additional Information
Form Liquid
Storage Instructions Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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