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EVI1 Rabbit mAb

Catalog Number:OM647737
OM647737
Discount Price
OM647737-100ul
100ul
OM647737-50ul
50ul
Product Profile
Product Name EVI1 Rabbit mAb
Antibody Type Primary Antibodies
Immunogen The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications IHCWB
WB:1:2000-1:10000
IHC:1:200-1:1000
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol MECOM
Gene Synonyms EVI1
MDS1
KMT8E
PRDM3
RUSAT2
MDS1-EVI1
AML1-EVI-1
Gene Full Name MDS1 and EVI1 complex locus
Gene Summary The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Molecular Weight(MW) 138 kDa
Cellular Localization Nucleus . Nucleus speckle . Cytoplasm .
Database Links
SwissProt ID Q03112
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-EVI1 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.

IHC

Human appendix was stained with anti-EVI1 Rabbit antibody.
Application Notes WB:1:2000-1:10000
IHC:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year (Do not lower than -25°C).
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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