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Anti-ATF4 antibody-HRP

Catalog Number:OM650051-HRP
Human;Mouse;Rat
WB;IHC
OM650051-HRP
Discount Price
OM650051-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-ATF4 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol ATF4
Gene Synonyms CREB2
TXREB
CREB-2
TAXREB67
Gene Full Name activating transcription factor 4
Gene Summary This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]
Molecular Weight(MW) 39kDa(observed:50kDa)
Source Rabbit
Cellular Localization Cell membrane, Cytoplasm, Cytoskeleton, Membrane, Nucleus
Database Links
SwissProt ID P18848
Application

WB

Western blot analysis using ATF4 antibody against Hepg2(1),Mcf-7(2),A549(3),Cos7(4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using ATF4 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ATF4 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ATF4 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using ATF4 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using ATF4 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using ATF4 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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