IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using PRKAB1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PRKAB1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PRKAB1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using PRKAB1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using PRKAB1 antibody with DAB staining.WB
Western blot analysis using PRKAB1 antibody against Mouse brain(1),Mouse intestine(2),Mouse testes(3), Mouse heart(4),Mouse stomach(5),Rat kidney (6),Rat lung(7) tissue.| Product Name | Anti-PRKAB1 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PRKAB1 |
|---|---|
| Gene Synonyms | AAKB1 AMPK HAMPKb |
| Gene Full Name | protein kinase AMP-activated non-catalytic subunit beta 1 |
| Gene Summary | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. |
| Molecular Weight(MW) | 30 kDa |
| Cellular Localization | Cytosol, nucleoplasm, nucleus, cytoplasm |
| SwissProt ID | Q9Y478 |
|---|
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using PRKAB1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PRKAB1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PRKAB1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using PRKAB1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using PRKAB1 antibody with DAB staining.
WB
Western blot analysis using PRKAB1 antibody against Mouse brain(1),Mouse intestine(2),Mouse testes(3), Mouse heart(4),Mouse stomach(5),Rat kidney (6),Rat lung(7) tissue.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
