WB
Western blot analysis using CTCF antibody against Mcf-7(1) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using CTCF antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human brain tissues using CTCF antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using CTCF antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using CTCF antibody with DAB staining.| Product Name | Anti-CTCF antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CTCF |
|---|---|
| Gene Synonyms | MRD21 FAP108 CFAP108 |
| Gene Full Name | CCCTC-binding factor |
| Gene Summary | This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| Molecular Weight(MW) | 83KD |
| Cellular Localization | Centromere, Chromosome, Nucleus |
| SwissProt ID | P49711 |
|---|
WB
Western blot analysis using CTCF antibody against Mcf-7(1) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using CTCF antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human brain tissues using CTCF antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using CTCF antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using CTCF antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
