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Anti-XRCC5 antibody-poly-HRP

Catalog Number:OM650350-poly-HRP
Human;Mouse;Rat
WB;IHC
OM650350-poly-HRP
Discount Price
OM650350-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-XRCC5 antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol XRCC5
Gene Synonyms KU80
KUB2
Ku86
NFIV
KARP1
KARP-1
Gene Full Name X-ray repair cross complementing 5
Gene Summary The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 83KD
Cellular Localization Chromosome, Nucleus
Database Links
SwissProt ID P13010
Application

WB

Western blot analysis using XRCC5 antibody against K562(1), MCF-7(2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using XRCC5 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using XRCC5 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using XRCC5 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using XRCC5 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using XRCC5 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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