| Product Name | Anti-Phospho-Ku80 (Ser145) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser145 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | XRCC5 |
|---|---|
| Gene Synonyms | KU80 KUB2 Ku86 NFIV KARP1 KARP-1 |
| Gene Full Name | X-ray repair cross complementing 5 |
| Gene Summary | The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008] |
| Alternative Names | 86 kDa subunit of Ku antigen ATP dependent DNA helicase 2 subunit 2 ATP dependent DNA helicase II 80 kDa subunit ATP dependent DNA helicase II 86 Kd subunit ATP dependent DNA helicase II ATP-dependent DNA helicase 2 subunit 2 ATP-dependent DNA helicase II 80 kDa subunit CTC box binding factor 85 kDa CTC box-binding factor 85 kDa subunit CTC85 CTCBF DNA repair protein XRCC5 KARP 1 KARP1 Ku 80 Ku autoantigen 80 kDa Ku80 Ku86 Ku86 autoantigen related protein 1 KUB 2 KUB2 Lupus Ku autoantigen protein p86 NFIV Nuclear factor IV Thyroid lupus autoantigen Thyroid-lupus autoantigen TLAA X ray repair complementing defective repair in Chinese hamster cells 5 (double strand break rejoining) X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) X-ray repair cross-complementing protein 5 Xray repair complementing defective repair in Chinese hamster cells 5 XRCC 5 XRCC5 XRCC5_HUMAN |
| Molecular Weight(MW) | 83 kDa |
| Cellular Localization | Chromosome, Nucleus. |
| SwissProt ID | P13010 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
