IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using Notch3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using Notch3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Notch3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using Notch3 antibody with DAB staining.WB
Western blot analysis using Notch3 antibody against Hela(1),Cos-7(2),K562(3),THP-1(4),A549(5),Nih3t3(6)cell .| Product Name | Anti-Notch3 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NOTCH3 |
|---|---|
| Gene Synonyms | IMF2 LMNS CASIL CADASIL CADASIL1 |
| Gene Full Name | notch receptor 3 |
| Gene Summary | This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 244kDa(observed：97kDa) |
| Cellular Localization | Cell membrane, Nucleus |
| SwissProt ID | Q9UM47 |
|---|
IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using Notch3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using Notch3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Notch3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using Notch3 antibody with DAB staining.
WB
Western blot analysis using Notch3 antibody against Hela(1),Cos-7(2),K562(3),THP-1(4),A549(5),Nih3t3(6)cell .| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
