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Anti-FTO antibody-HRP

Catalog Number:OM660410-HRP
Human;Mouse;Rat
WB;IHC
OM660410-HRP
Discount Price
OM660410-HRP-100ul
100ul
Product Profile
Product Name Anti-FTO antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol FTO
Gene Synonyms FTO
KIAA1752
Alpha-ketoglutarate-dependent dioxygenase FTO
Fat mass and obesity-associated protein
Gene Full Name FTO alpha-ketoglutarate dependent dioxygenase
Gene Summary This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Molecular Weight(MW) 58kDa(observed:55kDa)
Source Rabbit
Cellular Localization Nucleus, Cytoplasm
Database Links
SwissProt ID Q9C0B1
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using FTO antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using FTO antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using FTO antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using FTO antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using FTO antibody with DAB staining.

WB

Western blot analysis using FTO antibody against Hela(1),Hepg2(2),A549(3),Huvec(4),Cos-7(5),K562(6),Jurkat(7),T24(8),Raji(9) cell.

WB

Western blot analysis using FTO antibody against Rat stomach(1) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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