WB
Western blot analysis using Myc tag mouse monoclonal antibody against BSA-Myc lysate.IHC
Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using Myc tag antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded esophageal tissues using Myc tag antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded liver cancer tissues using Myc tag antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using Myc tag antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using Myc tag antibody with DAB staining.| Product Name | Anti-Myc tag antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant protein |
| Conjugation | poly-HRP |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | All |
| Purification | Affinity purified |
| Alternative Names | AU016757 antibody Avian myelocytomatosis viral oncogene homolog antibody bHLHe39 antibody c Myc antibody Cellular myelocytomatosis oncogene antibody Class E basic helix-loop-helix protein 39 antibody MGC105490 antibody MRTL antibody Myc antibody Myc protein antibody |
|---|---|
| Molecular Weight(MW) | 70-100kDa |
| Function | Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis . Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).Myc proteins are transcription factors that activate expression of many pro-proliferative genes through binding enhancer box sequences (E-boxes) and recruiting histone acetyltransferases (HATs). Myc is thought to function by upregulating transcript elongation of actively transcribed genes through the recruitment of elongation factors.[8] It can also act as a transcriptional repressor. By binding Miz-1 transcription factor and displacing the p300 co-activator, it inhibits expression of Miz-1 target genes. In addition, myc has a direct role in the control of DNA replication.[9] This activity could contribute to DNA amplification in cancer cells. |
| Cellular Localization | Nucleus nucleoplsm Nucleolus Cytoplasm chromosome |
WB
Western blot analysis using Myc tag mouse monoclonal antibody against BSA-Myc lysate.
IHC
Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using Myc tag antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded esophageal tissues using Myc tag antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded liver cancer tissues using Myc tag antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using Myc tag antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using Myc tag antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide.Purified antibody in PBS with 0.05% PC300. |
