IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using XIAP antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using XIAP antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using XIAP antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using XIAP antibody with DAB staining.WB
Western blot analysis using XIAP antibody against K562(1),A549(2),A431(3),Huvec(4),Nih3t3(5),Cos-7(6),C2C12(7),Hek293(8),Mcf-7(9) cell .| Product Name | Anti-XIAP antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | XIAP |
|---|---|
| Gene Synonyms | API3 ILP1 MIHA XLP2 BIRC4 IAP-3 hIAP3 hIAP-3 |
| Gene Full Name | X-linked inhibitor of apoptosis |
| Gene Summary | This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011] |
| Molecular Weight(MW) | 57kDa(observed：50kDa） |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, Nucleus |
| SwissProt ID | P98170 |
|---|
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using XIAP antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using XIAP antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using XIAP antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using XIAP antibody with DAB staining.
WB
Western blot analysis using XIAP antibody against K562(1),A549(2),A431(3),Huvec(4),Nih3t3(5),Cos-7(6),C2C12(7),Hek293(8),Mcf-7(9) cell .| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
