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Anti-p18 INK4c antibody

Catalog Number:OM660754
OM660754
Discount Price
OM660754-100ul
1~2 Week
100ul
OM660754-50ul
50ul
OM660754-20ul
1~2 Week
20ul
1~2 Week
Product Profile
Product Name Anti-p18 INK4c antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CDKN2C
Gene Synonyms INK4C
p18
p18-INK4C
p18-INK6
p18INK4c
Gene Full Name cyclin dependent kinase inhibitor 2C
Gene Summary The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
Alternative Names CDK6 inhibitor p18
CDKN2C
cyclin-dependent inhibitor
cyclin-dependent kinase 6 inhibitor
cyclin-dependent kinase 6 inhibitor p18
cyclin-dependent kinase inhibitor 2C (p18
inhibits CDK4)
p18-INK6
p18Ink4c
cell cycle inhibitor
Molecular Weight(MW) 18kDa
Source Rabbit
Cellular Localization Cytoplasm, cytosol, nucleus
Database Links
SwissProt ID P42773
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-10000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300,40% Glycerol.
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