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Anti-HSPB8/HSP22 antibody-HRP

Catalog Number:OM660919-HRP
Human;Mouse;Rat
WB;IHC
OM660919-HRP
Discount Price
OM660919-HRP-100ul
100ul
Product Profile
Product Name Anti-HSPB8/HSP22 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Recombinant protein
Conjugation HRP
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Mouse
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Purification Affinity purified
Target Information
Gene Symbol HSPB8
Gene Synonyms H11
HMN2
CMT2L
DHMN2
E2IG1
HMN2A
HMND2
HSP22
MFM13
HSPB8-N1
HSPB8-N2
Gene Full Name heat shock protein family B (small) member 8
Gene Summary The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 22kDa
Cellular Localization Cytoplasm,Nucleus.
Database Links
SwissProt ID Q9UJY1
Application

WB

Western blot analysis using HSPB8/HSP22 antibody against Mouse liver tissue(1) lysate .

IHC

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using HSPB8/HSP22 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Kidney tissues using HSPB8/HSP22 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded muscle tissues using HSPB8/HSP22 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded renal carcinoma tissues using HSPB8/HSP22 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.Purified antibody in PBS with 0.05% PC300.
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