| Gene Symbol |
TGFBI
|
| Gene Synonyms |
CSD CDB1 CDG2 CSD1 CSD2 CSD3 EBMD LCD1 BIGH3 CDGG1 |
| Gene Full Name |
transforming growth factor beta induced |
| Gene Summary |
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) |
75kDa |
| Source |
Rabbit |
| Cellular Localization |
Secreted, extracellular space, extracellular matrix |