| Product Name | Human TGFBI Recombinant protein |
|---|---|
| Species Reactivity | Human |
| Gene Symbol | TGFBI |
| Gene Synonyms | CSD CDB1 CDG2 CSD1 CSD2 CSD3 EBMD LCD1 BIGH3 CDGG1 |
| Gene Full Name | transforming growth factor beta induced |
| Gene Summary | This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. |
