ICC/IF
Immunofluorescence analysis of C2C12 cells using GPR30 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-GPR30 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | GPER1 |
|---|---|
| Gene Synonyms | 6330420K13Rik CEPR Ceprl CMKRL2 DRY12 FEG-1 GPCR-Br GPER GPR30 GPR41 LERGU LERGU2 LyGPR mER |
| Gene Full Name | G protein-coupled estrogen receptor 1 |
| Gene Summary | This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. [provided by RefSeq, Aug 2017] |
| Alternative Names | chemoattractant receptor-like 2 chemokine receptor-like 2 constitutively expressed peptide-like receptor constitutively expressed peptide-like receptor like flow-induced endothelial G-protein coupled receptor 1 G protein-coupled receptor 30 G-protein coupled estrogen receptor 1 G-protein coupled receptor 30 G-protein coupled receptor 41 GPR30 heptahelix receptor IL8-related receptor DRY12 leucine rich protein in GPR30 3'UTR leucine rich protein in GPR30 3'UTR (LERGU) lymphocyte-derived G-protein coupled receptor membrane estrogen receptor mER |
| Molecular Weight(MW) | 42kDa |
| Source | Rabbit |
| Cellular Localization | Mitochondrion,Nucleus,Endosome,Golgi apparatus,Endoplasmic reticulum,Cytoskeleton |
| SwissProt ID | Q99527 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using GPR30 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
