| Gene Symbol |
FOXO3
|
| Gene Synonyms |
1110048B16Rik 2010203A17Rik AF6q21 Afxh FKH1 FKHR Fkhr1 Fkhr2 FKHRL1 FKHRL1P2 FOXO1A FOXO2 FOXO3A |
| Gene Full Name |
forkhead box O3 |
| Gene Summary |
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| Alternative Names |
AFX AFX1 forkhead box O1a forkhead box O1A (rhabdomyosarcoma) forkhead box O3A Forkhead box protein O1A forkhead homolog (rhabdomyosarcoma) like 1 Forkhead in rhabdomyosarcoma forkhead in rhabdomyosarcoma-like 1 forkhead protein 1 forkhead protein FKHR2 forkhead Drosophila homolog of in rhabdomyosarcoma forkhead Drosophila homolog of in rhabdomyosarcoma-like 1 FOXO3A- FOXO4 member of FKHR-subclass forkhead/winged helix family MGC120490 MLLT7 |
| Molecular Weight(MW) |
71kDa |
| Source |
Rabbit |
| Cellular Localization |
Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus |