| Gene Symbol |
TFAP2A
|
| Gene Synonyms |
AP-2 Ap-2 (a) AP-2alpha Ap2 AP2alpha AP2TF BOFS Tcfap2a TFAP2 |
| Gene Full Name |
transcription factor AP-2 alpha |
| Gene Summary |
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009] |
| Alternative Names |
activating enhancer-binding protein 2 alpha activating enhancer-binding protein 2-alpha activator protein 2 AP-2 transcription factor DNA-binding protein (AP-2) ERF-1 FLJ51761 OTTHUMP00000214240 OTTHUMP00000214243 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| Molecular Weight(MW) |
48kDa |
| Source |
Rabbit |
| Cellular Localization |
Nucleus |