The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
Alternative Names
activating enhancer-binding protein 2 alpha activating enhancer-binding protein 2-alpha activator protein 2 AP-2 transcription factor DNA-binding protein (AP-2) ERF-1 FLJ51761 OTTHUMP00000214240 OTTHUMP00000214243 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)