ICC/IF
Immunofluorescence analysis of C2C12 cells using LIMPII antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-LIMPII antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SCARB2 |
|---|---|
| Gene Synonyms | 9330185J12Rik AMRF CD36L2 EPM4 HLGP85 LGP85 LIMP II LIMP-2 LIMPII MLGP85 SR-BII |
| Gene Full Name | scavenger receptor class B member 2 |
| Gene Summary | The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] |
| Alternative Names | 85 kDa lysosomal membrane sialoglycoprotein 85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2 CD 36 CD36 antigen (collagen type I receptor thrombospondin receptor)-like 2 CD36 antigen (collagen type I receptor thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) CD36 antigen-like 2 CD36 molecule LIMP II lysosome membrane protein II sCD 36 sCD36 soluble CD 36 soluble CD36 SR-B2 |
| Molecular Weight(MW) | 54kDa(observed：70kDa) |
| Source | Rabbit |
| Cellular Localization | Lysosome membrane |
| SwissProt ID | Q14108 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using LIMPII antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
