ICC/IF
Immunofluorescence analysis of NIH3T3 cells using MKL1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-MKL1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MRTFA |
|---|---|
| Gene Synonyms | AMKL BSAC FLMKL1 MAL MELODY MKL MKL1 MKL1met MRTF-A |
| Gene Full Name | myocardin related transcription factor A |
| Gene Summary | The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| Alternative Names | alternative protein MKL1 basic SAP and coiled-coil domains basic SAP coiled-coil transcription activator basic SAP and coiled-coil domain basic SAP and coiled-coil domain containing protein basic SAP coiled-coil domain transcriptional activator megakaryoblastic leukemia (translocation) 1 megakaryoblastic leukemia (translocation) 1 homolog megakaryoblastic leukemia 1 met megakaryoblastic leukemia 1 protein megakaryocytic acute leukemia protein megakaryocytic acute leukemia protein homolog mixed lineage leukemia MKL (megakaryoblastic leukemia)/myocardin-like 1 MKL/myocardin-like protein 1 MKL1 MKL1-elongated derivative of yield protein MRTF-A myocardial related transcription factor A |
| Molecular Weight(MW) | 99kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, Nucleus |
| SwissProt ID | Q969V6 |
|---|
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using MKL1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
