| Gene Symbol |
MRTFA
|
| Gene Synonyms |
AMKL BSAC FLMKL1 MAL MELODY MKL MKL1 MKL1met MRTF-A |
| Gene Full Name |
myocardin related transcription factor A |
| Gene Summary |
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| Alternative Names |
alternative protein MKL1 basic SAP and coiled-coil domains basic SAP coiled-coil transcription activator basic SAP and coiled-coil domain basic SAP and coiled-coil domain containing protein basic SAP coiled-coil domain transcriptional activator megakaryoblastic leukemia (translocation) 1 megakaryoblastic leukemia (translocation) 1 homolog megakaryoblastic leukemia 1 met megakaryoblastic leukemia 1 protein megakaryocytic acute leukemia protein megakaryocytic acute leukemia protein homolog mixed lineage leukemia MKL (megakaryoblastic leukemia)/myocardin-like 1 MKL/myocardin-like protein 1 MKL1 MKL1-elongated derivative of yield protein MRTF-A myocardial related transcription factor A |
| Molecular Weight(MW) |
99kDa |
| Source |
Rabbit |
| Cellular Localization |
Cytoplasm, Nucleus |