ICC/IF
Immunofluorescence analysis of A549 cells using SOCS1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-SOCS1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SOCS1 |
|---|---|
| Gene Synonyms | AISIMD CIS1 CISH1 Cish7 JAB SOCS-1 SSI-1 SSI1 TIP-3 TIP3 |
| Gene Full Name | suppressor of cytokine signaling 1 |
| Gene Summary | This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008] |
| Alternative Names | cytokine inducible SH2-containing protein 1 cytokine inducible SH2-containing protein 7 cytokine-inducible SH2 protein 1 JAK binding protein JAK2-binding protein SOCS-1 STAT induced SH3 protein 1 STAT-induced STAT inhibitor 1 Tec-interacting protein 3 |
| Molecular Weight(MW) | 24kDa |
| Source | Rabbit |
| Cellular Localization | Nucleus, Cytoplasmic vesicle |
| SwissProt ID | O15524 |
|---|
ICC/IF
Immunofluorescence analysis of A549 cells using SOCS1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
