WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-SOCS-1 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody. Lane 1: Raji Lane 2: HepG2IHC
Human kidney was stained with anti-SOCS-1 Rabbit antibody| Product Name | SOCS-1 Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG,K |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHCIPWB |
| IHC 1:200-1:400 WB 1:2000-1:10000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SOCS1 |
|---|---|
| Gene Synonyms | JAB CIS1 SSI1 TIP3 CISH1 SSI-1 TIP-3 AISIMD SOCS-1 |
| Gene Full Name | suppressor of cytokine signaling 1 |
| Gene Summary | This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008] |
| Alternative Names | SOCS1 SSI1 TIP3 Suppressor of cytokine signaling 1 SOCS-1 JAK-binding protein JAB STAT-induced STAT inhibitor 1 SSI-1 Tec-interacting protein 3 TIP-3 |
| Molecular Weight(MW) | 24kDa(Observed band size: 22kDa) |
| Cellular Localization | Cytoplasmic vesicle,Nucleus |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-SOCS-1 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody. Lane 1: Raji Lane 2: HepG2
IHC
Human kidney was stained with anti-SOCS-1 Rabbit antibody| Application Notes | IHC 1:200-1:400 WB 1:2000-1:10000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year (Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
