| Product Name | Anti-DDX3X antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | DDX3X |
|---|---|
| Gene Synonyms | CAP-Rf D1Pas1-rs2 DBX DDX14 DDX3 Fin14 HLP2 MRX102 MRXSSB |
| Gene Full Name | DEAD-box helicase 3 X-linked |
| Gene Summary | The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] |
| Alternative Names | D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3 D1Pas1-related sequence 2 DEAD (Asp-Glu-Ala-Asp) box helicase 3 X-linked DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 X-linked DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3 DEAD box protein 3 X-chromosomal DEAD box RNA helicase DEAD3 DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2) DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 X-linked DEAD/H box-3 embryonic RNA helicase fibroblast growth factor inducible 14 FIN14 helicase-like protein 2 mDEAD3 |
| Molecular Weight(MW) | 73kDa |
| Cellular Localization | Nucleus speckle, Cytoplasm |
| SwissProt ID | O00571 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
