| Product Name | Anti-Phospho-DDX3 (Ser102) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser102 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DDX3X |
|---|---|
| Gene Synonyms | DBX DDX3 HLP2 DDX14 CAP-Rf MRX102 MRXSSB |
| Gene Full Name | DEAD-box helicase 3 X-linked |
| Gene Summary | The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] |
| Alternative Names | ATP dependent RNA helicase DDX3X ATP-dependent RNA helicase DDX3X CAP Rf DBX DDX14 DDX3X DDX3X_HUMAN DEAD (Asp Glu Ala Asp) box polypeptide 3 X linked DEAD (Asp-Glu-Ala-Asp) box helicase 3 X-linked DEAD box DEAD box protein 3 DEAD box protein 3 X-chromosomal DEAD box X isoform DEAD box X isoform DEAD/H (Asp Glu Ala Asp/His) box polypeptide 3 DEAD/H box 3 DEAD/H box 3 X-linked Helicase like protein 2 Helicase-like protein 2 HLP2 X isoform X-chromosomal |
| Molecular Weight(MW) | 73 kDa |
| Cellular Localization | Cell membrane,Cell projection,Cytoplasm,Cytoskeleton,Inflammasome. |
| SwissProt ID | O00571 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
