| Gene Symbol |
TNFSF13B
|
| Gene Synonyms |
BAFF BLYS CD257 D8Ertd387e TALL-1 TALL1 THANK TNFSF20 TNLG7A ZTNF4 |
| Gene Full Name |
TNF superfamily member 13b |
| Gene Summary |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011] |
| Alternative Names |
ApoL related ligand TALL-1 b cell-activating factor B-cell activating factor B-cell-activating factor B-lymphocyte stimulator BAFF TNF family BAFF TNFalpha homolog delta BAFF Delta4 BAFF dendritic cell-derived TNF-like molecule epididymis secretory sperm binding protein TNF and ApoL-related leukocyte expressed ligand 1 TNF family member TNF homolog that activates apoptosis TNF ligand superfamily member TNF-like cytokine TNFSF13B tumor necrosis factor (ligand) superfamily member 13b tumor necrosis factor (ligand) superfamily member 20 tumor necrosis factor ligand 7A tumor necrosis factor superfamily member 13b tumor necrosis factor-like protein ZTNF4 |
| Molecular Weight(MW) |
31kDa(observed:35kDa) |
| Cellular Localization |
Secreted, Cell membrane |