| Gene Symbol |
CACNA1B
|
| Gene Synonyms |
alpha(1B) BIII CACNL1A5 CACNN Cav2.2 Cchn1a DYT23 NEDNEH |
| Gene Full Name |
calcium voltage-gated channel subunit alpha1 B |
| Gene Summary |
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
| Alternative Names |
alpha1B-a brain calcium channel III CACHA1B calcium channel alpha12.2 subunit calcium channel L type alpha-1 polypeptide calcium channel voltage-dependent L type alpha 1B subunit calcium channel voltage-dependent N type alpha 1B subunit calcium channel voltage-dependent N type alpha 1B subunit BIII Cav2.2 voltage-gated Ca2+ channel ion channel CACNA1B Cav2 2 voltage gated N-type calcium channel Ca(v)2.2 voltage-dependent N-type calcium channel subunit alpha-1B-like voltage-gated calcium channel alpha subunit Cav2.2 voltage-gated calcium channel subunit alpha Cav2.2 |
| Molecular Weight(MW) |
262kDa |
| Cellular Localization |
Membrane |