| Product Name | Anti-GFRA2 antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | GFRA2 |
|---|---|
| Gene Synonyms | GDNFRB NRTNR-ALPHA NTNRA RETL2 TRNR2 |
| Gene Full Name | GDNF family receptor alpha 2 |
| Gene Summary | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| Alternative Names | GDNF family receptor alpha 2b GDNF family receptor alpha 2c GDNF re GDNF receptor beta GDNFR-alpha-2 GDNFR-beta GFR alpha 2 GFR alpha-2b GFR a-2b GFR alpha-2c GFR a-2c GFR-alpha 2 GFR-alpha-2 Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 glial cell line derived neurotrophic factor receptor beta HpV18gp1 neurturin receptor alpha non-signalling receptor for GDNF NRTNR-alpha NTNR-alpha PI-linked cell-surface accessory protein RET ligand 2 TGF-beta related neurotrophic factor receptor 2 neurturin/GDNF receptor TGF-beta related neurotrophic factor receptor 2 TRN receptor GPI-anchored TGF-beta-related neurotrophic factor receptor 2 TRN receptor GPI-anchored tyrosine kinase receptor ligand 2 |
| Molecular Weight(MW) | 51kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | O00451 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
