| Gene Symbol |
SNX1
|
| Gene Synonyms |
HsT17379
VPS5 |
| Gene Full Name |
sorting nexin 1 |
| Gene Summary |
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| Alternative Names |
MGC8664
SNX1 splice variant
SNX1A
sorting nexin 1A |
| Molecular Weight(MW) |
59kDa（observed：72kDa） |
| Cellular Localization |
Endosome membrane,Golgi apparatus, trans-Golgi network membrane,Early endosome membrane,Cell projection, lamellipodium |
