This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Alternative Names
CDC-related protein kinase p58 cell division cycle 2 homolog-like 1 cell division cycle 2 homolog-like 2 cell division cycle 2-like 1 cell division cycle 2-like 1 (PITSLRE proteins) cell division cycle 2-like 2 cell division cycle 2-like 2 (PITSLRE proteins) cell division cycle 2-like protein kinase 1 cell division cycle 2-like protein kinase 2 cell division protein kinase 11 cell division protein kinase 11A cell division protein kinase 11B cyclin-dependent kinase 11 galactosyltransferase-associated protein kinase p58/GTA GR specific protein kinase p58 CLK-1 PITSLRE B PITSLRE proteins PITSLRE serine/threonine-protein kinase CDC2L1 PITSLRE serine/threonine-protein kinase CDC2L2