ICC/IF
Immunofluorescence analysis of NIH3T3 cells using C3 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Product Name | Anti-C3 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | C3 |
|---|---|
| Gene Synonyms | AHUS5 ARMD9 ASP C3 C3a C3b C3d CPAMD1 HEL-S-62p HSE-MSF Plp |
| Gene Full Name | complement C3 |
| Gene Summary | Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015] |
| Alternative Names | acylation stimulating protein acylation-stimulating protein cleavage product C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 C3 convertase cleavage product C3a anaphylatoxin complement 3 complement C3 protein (GPC3) precursor complement component 3 complement component 3d complement component C3 complement component C3 precursor complement component C3a complement component C3b complement component C3d complement factor 3 epididymis secretory sperm binding protein Li 62p prepro-C3 preprocomplement component C3 |
| Molecular Weight(MW) | 187kDa |
| Cellular Localization | Secreted;Cell surface |
| SwissProt ID | P01024 |
|---|
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using C3 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
